GTX88450
TRC8 antibody, C-term
Cannot supply to this region.
- SKU:
- GTX88450
- Additional Names:
- ring finger protein 139 , HRCA1 , RCA1 , TRC8
- Application:
- WB, IHC-P
- Concentration:
- 0.50 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Ammonium Sulfate Precipitated; Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Goat
- Reactivities:
- Human
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence C-HTGAAAEEFNDDT, from the C Terminus of the protein sequence according to NP_009149.2.
- Uniprot:
- Q8WU17
- Synonyms:
- E3 ubiquitin-protein ligase RNF139;HRCA1;multiple membrane spanning receptor TRC8;patched related protein translocated in renal cancer;RCA1;RING finger protein 139;RING-type E3 ubiquitin transferase RNF139;translocation in renal carcinoma on chromosome 8 protein;translocation in renal carcinoma, chromosome 8;TRC8
- Extra Details:
- The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice