TRC8 blocking peptide

Cannot supply to this region.

SKU:: GTX88450-PEP
Additional Names:: Ring Finger Protein 139 , Hrca1 , Rca1 , Trc8 , Rnf139
Physical State:: Lyophilized
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Buffer:: Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
Immunogen:: ring finger protein 139
Species:: Human
Synonyms:: E3 ubiquitin-protein ligase RNF139;HRCA1;multiple membrane spanning receptor TRC8;patched related protein translocated in renal cancer;RCA1;RING-type E3 ubiquitin transferase RNF139;translocation in renal carcinoma on chromosome 8 protein;translocation in renal carcinoma, chromosome 8;TRC8
Extra Details:: The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. [provided by RefSeq, Jul 2008]