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  2. Polyclonal

GTX88448

CHN2 antibody, C-term

Cannot supply to this region.

SKU:
GTX88448
Additional Names:
chimerin 2 , ARHGAP3 , BCH , CHN2-3 , RHOGAP3
Application:
IHC-P
Concentration:
0.50 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Ammonium Sulfate Precipitated; Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Goat
Reactivities:
Human
Buffer:
TBS, 0.5% BSA, 0.02% Sodium azide.
Immunogen:
Peptide with sequence C-QILIENEDVLF, from the C Terminus of the protein sequence according to NP_001035025.1; NP_004058.1.
Uniprot:
P52757
Synonyms:
ARHGAP3;BCH;beta-chimaerin;beta-chimerin;beta3-chimaerin;chimerin (chimaerin) 2;chimerin, beta-2;chimerin, testis-specific;CHN2-3;Rho GTPase-activating protein 3;rho-GTPase-activating protein 3;RHOGAP3
Extra Details:
This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that contains a phorbol-ester/diacylglycerol (DAG)-type zinc finger, a Rho-GAP domain, and an SH2 domain. The encoded protein translocates from the cytosol to the Golgi apparatus membrane upon binding by diacylglycerol (DAG). Activity of this protein is important in cell proliferation and migration, and expression changes in this gene have been detected in cancers. A mutation in this gene has also been associated with schizophrenia in men. Alternative transcript splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, May 2014]
Shipping Conditions:
Blue Ice