GTX88408
PSMB10 antibody, Internal
Cannot supply to this region.
- SKU:
- GTX88408
- Additional Names:
- proteasome subunit beta 10 , LMP10 , MECL1 , beta2i
- Application:
- WB, IHC-P
- Concentration:
- 0.50 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Ammonium Sulfate Precipitated; Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Goat
- Reactivities:
- Human
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence C-PTEPVKRSGRYH, from the internal region of the protein sequence according to NP_002792.1.
- Uniprot:
- P40306
- Synonyms:
- beta2i;LMP10;low molecular mass protein 10;macropain subunit MECl-1;MECL1;multicatalytic endopeptidase complex subunit MECl-1;PRAAS5;proteasome (prosome, macropain) subunit, beta type, 10;proteasome catalytic subunit 2i;proteasome MECl-1;proteasome subunit beta 10;proteasome subunit beta 7i;proteasome subunit beta type-10;proteasome subunit beta-2i;proteasome subunit beta2i;proteasome subunit MECL1
- Extra Details:
- The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice