GTX88232
RNF7 antibody, Internal
Cannot supply to this region.
- SKU:
- GTX88232
- Additional Names:
- ring finger protein 7 , CKBBP1 , ROC2 , SAG , rbx2
- Application:
- WB
- Concentration:
- 0.50 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Ammonium Sulfate Precipitated; Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Goat
- Reactivities:
- Human
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence DACLRCQAENKQE, from the internal region of the protein sequence according to NP_055060.1.
- Uniprot:
- Q9UBF6
- Synonyms:
- CKBBP1;CKII beta-binding protein 1;rbx2;regulator of cullins 2;RING finger protein 7;RING-box protein 2;ROC2;SAG;sensitive to apoptosis gene protein;sensitive to apoptosis, zinc RING finger protein SAG, regulator of cullins 2;zinc RING finger protein SAG
- Extra Details:
- The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice