GTX88124
LARGE (aa421-433) antibody, Internal
Cannot supply to this region.
- SKU:
- GTX88124
- Additional Names:
- LARGE xylosyl- and glucuronyltransferase 1 , LARGE , MDC1D , MDDGA6 , MDDGB6
- Application:
- WB
- Concentration:
- 0.50 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Ammonium Sulfate Precipitated; Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Goat
- Reactivities:
- Human
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence C-SEADVNSENLQKQ, from the internal region of the protein sequence according to NP_004728.1.
- Uniprot:
- O95461
- Synonyms:
- acetylglucosaminyltransferase-like 1A;acetylglucosaminyltransferase-like protein;Glycosyltransferase-like protein;glycosyltransferase-like protein LARGE1;LARGE;LARGE xylosyl- and glucuronyltransferase 1;MDC1D;MDDGA6;MDDGB6
- Extra Details:
- This gene encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. The protein encoded by this gene is the glycotransferase that adds the final xylose and glucuronic acid to alpha-dystroglycan and thereby allows alpha-dystroglycan to bind ligands including laminin 211 and neurexin. Mutations in this gene cause several forms of congenital muscular dystrophy characterized by cognitive disability and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2018]
- Shipping Conditions:
- Blue Ice