GTX88103
IL12 Receptor beta1 antibody, Internal
Cannot supply to this region.
- SKU:
- GTX88103
- Additional Names:
- interleukin 12 receptor subunit beta 1 , CD212 , IL-12R-BETA1 , IL12RB , IMD30
- Application:
- WB
- Concentration:
- 0.50 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Ammonium Sulfate Precipitated; Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Goat
- Reactivities:
- Human
- Buffer:
- TBS, 0.5% BSA, 0.02% Sodium azide.
- Immunogen:
- Peptide with sequence C-HVSVKNHSLDSVS, from the internal region of the protein sequence according to NP_005526.1.
- Uniprot:
- P42701
- Synonyms:
- CD212;cluster of differentiation 212;IL-12 receptor beta component;IL-12 receptor subunit beta-1;IL-12R subunit beta-1;IL-12R-BETA1;IL12RB;IMD30;interleukin 12 receptor, beta 1;interleukin-12 receptor beta-1 chain;interleukin-12 receptor subunit beta-1
- Extra Details:
- The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
- Shipping Conditions:
- Blue Ice