GTX88059-PEP
ARHGDIB blocking peptide
Cannot supply to this region.
- SKU:
- GTX88059-PEP
- Additional Names:
- Rho Gdp Dissociation Inhibitor Beta , D4 , Gdia2 , Gdid4 , Lygdi , Ly-Gdi , Rap1Gn1 , Rhogdi2 , Arhgdib
- Physical State:
- Lyophilized
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Buffer:
- Reconstitute with 200ul distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
- Immunogen:
- Rho GDP dissociation inhibitor (GDI) beta
- Species:
- Human
- Synonyms:
- D4;GDIA2;GDID4;Ly-GDI;LYGDI;RAP1GN1;Rho GDI 2;Rho GDP dissociation inhibitor (GDI) beta;rho GDP-dissociation inhibitor 2;rho-GDI beta;RhoGDI2
- Extra Details:
- Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).[supplied by OMIM, Dec 2010]
- Shipping Conditions:
- Blue Ice