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  2. Polyclonal

GTX87701

SCN7A antibody

Cannot supply to this region.

SKU:
GTX87701
Additional Names:
NaG , Nav2.1 , Nav2.2 , SCN6A , SCN7A , sodium voltagegated channel alpha subunit 7 , sodium voltage-gated channel alpha subunit 7
Application:
IF, ICC
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
Immunogen:
The antiserum was produced against synthesized peptide derived from human SCN7A (771-820).
Uniprot:
Q01118
Synonyms:
NaG;Nav2.1;Nav2.2;putative voltage-gated sodium channel subunit alpha Nax;SCN6A;sodium channel protein cardiac and skeletal muscle subunit alpha;sodium channel protein type 7 subunit alpha;sodium channel protein type VII subunit alpha;sodium channel, voltage-gated, type VI, alpha polypeptide;sodium channel, voltage-gated, type VII, alpha subunit;voltage-dependent sodium channel alpha subunit
Extra Details:
This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011]
Shipping Conditions:
Blue Ice