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  2. Polyclonal

GTX87530

JIP3 antibody

Cannot supply to this region.

SKU:
GTX87530
Additional Names:
JIP3 , JSAP1 , MAPK8IP3 , SYD2 , mitogenactivated protein kinase 8 interacting protein 3 , syd , mitogen-activated protein kinase 8 interacting protein 3
Application:
WB, IF, ICC
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
Immunogen:
The antiserum was produced against synthesized peptide derived from human JIP3 (621-670).
Uniprot:
Q9UPT6
Synonyms:
C-jun-amino-terminal kinase interacting protein 3;C-Jun-amino-terminal kinase-interacting protein 3;homolog of Drosophila Sunday driver 2;JIP-3;JIP3;JNK MAP kinase scaffold protein 3;JNK-interacting protein 3;JNK/SAPK-associated protein-1;JNK/stress-activated protein kinase-associated protein 1;JSAP1;Mitogen-activated protein kinase 8-interacting protein 3;NEDBA;syd;SYD2
Extra Details:
The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Blue Ice