GTX87529
LATS2 antibody
Cannot supply to this region.
- SKU:
- GTX87529
- Additional Names:
- KPM , LATS2 , large tumor suppressor kinase 2
- Application:
- IHC-P, IF, ICC
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human LATS2 (541-590).
- Uniprot:
- Q9NRM7
- Synonyms:
- kinase phosphorylated during mitosis protein;KPM;large tumor suppressor homolog 2;LATS (large tumor suppressor, Drosophila) homolog 2;LATS, large tumor suppressor, homolog 2;serine/threonine kinase KPM;serine/threonine-protein kinase kpm;serine/threonine-protein kinase LATS2;warts-like kinase
- Extra Details:
- This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice