GTX87171
NECAB3 antibody
Cannot supply to this region.
- SKU:
- GTX87171
- Additional Names:
- APBA2BP , EFCBP3 , NECAB3 , NIP1 , Nterminal EFhand calcium binding protein 3 , STIP3 , SYTIP2 , XB51 , dJ63M2.4 , dJ63M2.5 , N-terminal EF-hand calcium binding protein 3
- Application:
- WB, IF, ICC
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human NECAB3 (321-370).
- Uniprot:
- Q96P71
- Synonyms:
- amyloid beta (A4) precursor protein-binding, family A, member 2 binding protein;amyloid beta A4 protein-binding family A member 2-binding protein;Amyloid-beta A4 protein-binding family A member 2-binding protein;APBA2BP;dJ63M2.4;dJ63M2.5;EF-hand calcium binding protein 3;EFCBP3;N-terminal EF-hand calcium-binding protein 3;Nek2-interacting protein 1;neuronal calcium-binding protein 3;neuronal calcium-binding protein NECAB3;NIP1;STIP3;synaptotagmin interacting protein 2;synaptotagmin interacting protein STIP3;SYTIP2;X11L-binding protein 51;XB51
- Extra Details:
- The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice