GTX87150
TBX1 antibody
Cannot supply to this region.
- SKU:
- GTX87150
- Additional Names:
- CAFS , CATCH22 , CTHM , DGCR , DGS , DORV , TBX1 , TBX1C , TGA , Tbox 1 , VCF , VCFS , T-box 1
- Application:
- WB, IF, ICC
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human TBX1 (311-360).
- Uniprot:
- O43435
- Synonyms:
- brachyury;CAFS;CATCH22;CTHM;DGCR;DGS;DORV;T-box 1 transcription factor C;T-box transcription factor TBX1;TBX1C;Testis-specific T-box protein;TGA;VCF;VCFS
- Extra Details:
- This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product shares 98% amino acid sequence identity with the mouse ortholog. DiGeorge syndrome (DGS)/velocardiofacial syndrome (VCFS), a common congenital disorder characterized by neural-crest-related developmental defects, has been associated with deletions of chromosome 22q11.2, where this gene has been mapped. Studies using mouse models of DiGeorge syndrome suggest a major role for this gene in the molecular etiology of DGS/VCFS. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- Shipping Conditions:
- Blue Ice