GTX87042
SnoN antibody
Cannot supply to this region.
- SKU:
- GTX87042
- Additional Names:
- SKI like protooncogene , SKIL , SNO , SnoA , SnoI , SnoN , SKI-like proto-oncogene
- Application:
- WB
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human SnoN (616-665).
- Uniprot:
- P12757
- Synonyms:
- SKI-like oncogene;ski-like protein;Ski-related oncogene;ski-related oncogene snoN;Ski-related protein;SNO;SnoA;SnoI;SnoN
- Extra Details:
- The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
- Shipping Conditions:
- Blue Ice