GTX86986
MKL1 antibody
Cannot supply to this region.
- SKU:
- GTX86986
- Additional Names:
- BSAC , MAL , MKL1 , MRTFA , megakaryoblastic leukemia (translocation) 1
- Application:
- WB
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human MKL1 (8-59).
- Uniprot:
- Q969V6
- Synonyms:
- basic, SAP and coiled-coil domain;BSAC;MAL;megakaryoblastic leukemia (translocation) 1;megakaryoblastic leukemia 1 protein;megakaryocytic acute leukemia protein;MKL;MKL/myocardin-like protein 1;MKL1;MRTF-A;myocardin-related transcription factor A
- Extra Details:
- The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
- Shipping Conditions:
- Blue Ice