GTX86983
MBTPS2 antibody
Cannot supply to this region.
- SKU:
- GTX86983
- Additional Names:
- BRESEK , IFAP , KFSD , KFSDX , MBTPS2 , OLMSX , S2P , membrane bound transcription factor peptidase, site 2
- Application:
- IF, ICC
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human MBTPS2 (301-350).
- Uniprot:
- O43462
- Synonyms:
- BRESEK;endopeptidase S2P;IFAP;keratosis follicularis spinulosa decalvans;KFSD;KFSDX;membrane-bound transcription factor protease, site 2;membrane-bound transcription factor site-2 protease;OI19;OLMSX;S2P;site-2 protease;SREBPs intramembrane protease;sterol regulatory element-binding proteins intramembrane protease
- Extra Details:
- This gene encodes a intramembrane zinc metalloprotease, which is essential in development. This protease functions in the signal protein activation involved in sterol control of transcription and the ER stress response. Mutations in this gene have been associated with ichthyosis follicularis with atrichia and photophobia (IFAP syndrome); IFAP syndrome has been quantitatively linked to a reduction in cholesterol homeostasis and ER stress response.[provided by RefSeq, Aug 2009]
- Shipping Conditions:
- Blue Ice