GTX86929
MASP1 (cleaved Arg448) antibody
Cannot supply to this region.
- SKU:
- GTX86929
- Additional Names:
- 3MC1 , CRARF , CRARF1 , MAP1 , MASP , MASP1 , MASP3 , MAp44 , PRSS5 , RaRF , mannan binding lectin serine peptidase 1 , mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
- Application:
- WB
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- The antiserum was produced against synthesized peptide derived from human MASP1 (399-448).
- Uniprot:
- P48740
- Synonyms:
- 3MC1;C4/C2 activating component of Ra-reactive factor;complement factor MASP-3;complement-activating component of Ra-reactive factor;CRARF;CRARF1;mannan binding lectin serine peptidase 1;mannan-binding lectin serine protease 1;mannose-associated serine protease 1;mannose-binding lectin-associated serine protease 1;mannose-binding protein-associated serine protease;MAP-1;MAP1;MAp44;MASP;MASP-3;MASP3;PRSS5;Ra-reactive factor serine protease p100;RaRF;serine protease 5
- Extra Details:
- This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]
- Shipping Conditions:
- Blue Ice