Thyroid Hormone Receptor beta (cleaved Arg327) antibody

Cannot supply to this region.

SKU:: GTX86914
Additional Names:: CERBA2 , CERBABETA , ERBA2 , GRTH , NR1A2 , PRTH , THR1 , THRB , THRB1 , THRB2 , thyroid hormone receptor beta , Thyroid Hormone Receptor beta , thyroid hormone receptor, beta
Application:: WB
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: The antiserum was produced against synthesized peptide derived from human Thyroid Hormone Receptor beta (278-327).
Uniprot:: P10828
Synonyms:: C-ERBA-2;C-ERBA-BETA;ERBA2;GRTH;NR1A2;nuclear receptor subfamily 1 group A member 2;oncogene ERBA2;PRTH;THR1;THRB1;THRB2;thyroid hormone nuclear receptor beta variant 1;thyroid hormone receptor beta;thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian);TRbeta
Extra Details:: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]

Shipping Conditions:: Blue Ice