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  2. Polyclonal

GTX86885

ADAM17 (cleaved Arg215) antibody

Cannot supply to this region.

SKU:
GTX86885
Additional Names:
ADAM metallopeptidase domain 17 , ADAM17 , ADAM18 , CD156B , CSVP , NISBD , NISBD1 , TACE
Application:
WB
Physical State:
Liquid
Species Reactivity:
Human, Rat
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Rat
Buffer:
PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
Immunogen:
The antiserum was produced against synthesized peptide derived from human ADAM17 (196-245).
Uniprot:
P78536
Synonyms:
a disintegrin and metalloproteinase 17;ADAM metallopeptidase domain 18;ADAM18;cartilage snake venom-like protease;CD156B;CSVP;disintegrin and metalloproteinase domain-containing protein 17;NISBD;NISBD1;snake venom-like protease;TACE;TNF-alpha convertase;TNF-alpha convertase enzyme;TNF-alpha converting enzyme;TNF-alpha-converting enzyme;tumor necrosis factor, alpha, converting enzyme
Extra Details:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq, Jul 2008]
Shipping Conditions:
Blue Ice