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  2. Polyclonal

GTX86757

FYN (phospho Tyr530) antibody

Cannot supply to this region.

SKU:
GTX86757
Additional Names:
FYN proto-oncogene, Src family tyrosine kinase , SLK , SYN , p59-FYN
Application:
WB, IHC-P
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified; Sequential Chromatography
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
Immunogen:
The antiserum was produced against synthesized peptide derived from human Fyn around the phosphorylation site of Tyr530.
Synonyms:
c-syn protooncogene;FYN oncogene related to SRC, FGR, YES;OKT3-induced calcium influx regulator;p59-FYN;proto-oncogene c-Fyn;proto-oncogene Syn;SLK;src-like kinase;src/yes-related novel;SYN;tyrosine kinase p59fyn(T);tyrosine-protein kinase Fyn
Extra Details:
Implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels, with isoform 2 showing the greater ability to mobilize cytoplasmic calcium in comparison to isoform 1. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Blocks axon outgrowth and attraction induced by NTN1 by phosphorylating its receptor DDC.
Shipping Conditions:
Blue Ice