GTX85496
IL23 antibody
Cannot supply to this region.
- SKU:
- GTX85496
- Additional Names:
- interleukin 23 subunit alpha , IL-23 , IL-23A , IL23P19 , P19 , SGRF
- Application:
- ELISA, WB, IHC-P, IF, ICC
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- IL-23 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human IL-23.The immunogen is located within the last 50 amino acids of IL-23.
- Uniprot:
- Q9NPF7
- Synonyms:
- IL-23;IL-23 subunit alpha;IL-23-A;IL-23A;IL-23p19;IL23P19;interleukin 23 p19 subunit;interleukin 23, alpha subunit p19;interleukin-23 subunit alpha;interleukin-23 subunit p19;interleukin-six, G-CSF related factor;JKA3 induced upon T-cell activation;P19;SGRF
- Extra Details:
- Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.
- Shipping Conditions:
- Blue Ice