GTX85487
TRBP1 antibody
Cannot supply to this region.
- SKU:
- GTX85487
- Additional Names:
- TAR (HIV-1) RNA binding protein 1 , TRM3 , TRMT3 , TRP-185 , TRP185
- Application:
- ELISA, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- TRBP1 antibody was raised against a 17 amino acid synthetic peptide from near the center of human TRBP1.The immunogen is located within amino acids 1310 - 1360 of TRBP1.
- Uniprot:
- Q13395
- Synonyms:
- probable methyltransferase TARBP1;TAR (HIV) RNA-binding protein 1;TAR RNA loop binding protein;TAR RNA-binding protein 1;TAR RNA-binding protein of 185 kDa;TRM3;TRMT3;tRNA methyltransferase 3 homolog;TRP-185;TRP185
- Extra Details:
- The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1alpha (EF-1alpha), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB). TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.
- Shipping Conditions:
- Blue Ice