GTX85460
NF-L antibody
Cannot supply to this region.
- SKU:
- GTX85460
- Additional Names:
- neurofilament light , CMT1F , CMT2E , CMTDIG , NF-L , NF68 , NFL , PPP1R110
- Application:
- IHC, WB, IHC-P, IF, ICC
- Concentration:
- 300 ug/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- 2-8[o]C Do not freeze.
- Supplier:
- Genetex
- Host:
- Chicken/Avian
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 1% BSA, 0.02% Sodium azide.
- Immunogen:
- Chickens were immunized with three synthetic peptide / keyhole limpet hemocyanin (KLH) conjugates. These synthetic peptides corresponded to different regions of the NF-L gene product, but are shared between the human (P07196, NCBI) and mouse (P08551, NCBI) protein sequences.
- Uniprot:
- P07196
- Synonyms:
- 68 kDa neurofilament protein;CMT1F;CMT2E;CMTDIG;light molecular weight neurofilament protein;neurofilament light polypeptide;neurofilament protein, light chain;neurofilament subunit NF-L;neurofilament triplet L protein;neurofilament, light polypeptide 68kDa;NF-L;NF68;NFL;PPP1R110;protein phosphatase 1, regulatory subunit 110
- Extra Details:
- Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
- Shipping Conditions:
- Blue Ice