GTX85418
Cathelicidin antibody
Cannot supply to this region.
- SKU:
- GTX85418
- Additional Names:
- cathelicidin antimicrobial peptide , CAP-18 , CAP18 , CRAMP , FALL-39 , FALL39 , HSD26 , LL37
- Application:
- ELISA, WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Cathelicidin antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of the human Cathelicidin.The immunogen is located within amino acids 50 - 100 of Cathelicidin.
- Uniprot:
- P49913
- Synonyms:
- 18 kDa cationic antimicrobial protein;CAP-18;CAP18;cathelicidin antimicrobial peptide;CRAMP;epididymis secretory sperm binding protein;FALL-39;FALL39;HSD26;LL37
- Extra Details:
- One component of host defense at mucosal surfaces is epithelial-derived antimicrobial peptides. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Finally, Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
- Shipping Conditions:
- Blue Ice