GTX85413
Slitrk5 antibody
Cannot supply to this region.
- SKU:
- GTX85413
- Additional Names:
- SLIT and NTRK like family member 5 , LRRC11 , bA364G4.2
- Application:
- ELISA, WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Slitrk5 antibody was raised against a 15 amino acid synthetic peptide from near the center of human Slitrk5.The immunogen is located within amino acids 330 - 380 of Slitrk5.
- Uniprot:
- O94991
- Synonyms:
- bA364G4.2;leucine rich repeat containing 11;leucine-rich repeat-containing protein 11;LRRC11;SLIT and NTRK-like protein 5;slit and trk like gene 5
- Extra Details:
- SLIT and NTRK-like family 5 (Slitrk5) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk5 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth. This antibody is predicted to have no cross-reactivity to other Slitrk proteins.
- Shipping Conditions:
- Blue Ice