GTX85396
DLGAP1 antibody
Cannot supply to this region.
- SKU:
- GTX85396
- Additional Names:
- DLG associated protein 1 , DAP-1 , DAP-1-ALPHA , DAP-1-BETA , DAP1 , DLGAP1A , DLGAP1B , GKAP , SAPAP1
- Application:
- ELISA, WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- DLGAP1 antibody was raised against a 18 amino acid synthetic peptide from near the center of human DLGAP1.The immunogen is located within amino acids 640 - 690 of DLGAP1.
- Uniprot:
- O14490
- Synonyms:
- DAP-1;DAP-1-ALPHA;DAP-1-BETA;DAP1;discs large homolog associated protein 1;disks large-associated protein 1;DLGAP1A;DLGAP1B;GKAP;guanylate kinase-associated protein;PSD-95/SAP90 binding protein 1;PSD-95/SAP90-binding protein 1;SAP90/PSD-95-associated protein 1;SAPAP1
- Extra Details:
- SAP90/PSD-95-associated protein 1 (SAPAP1, also known as DLGAP1 or GKAP) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP1 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2). SAPAP1 mRNA is targeted to cell bodies in a similar manner to SAPAP2 and -4, whereas SAPAP3 mRNA is detected mainly in cell bodies. SAPAP1 protein however, is targeted to the synapse and is not reliant on the synaptic localization of PSD-95 or the synaptic scaffolding molecule (S-SCAM). At least three isoforms of SAPAP1 are known to exist. This SAPAP1 antibody will not cross-react with other SAPAP proteins.
- Shipping Conditions:
- Blue Ice