GTX85374
MEX3C antibody
Cannot supply to this region.
- SKU:
- GTX85374
- Additional Names:
- mex-3 RNA binding family member C , BM-013 , MEX-3C , RKHD2 , RNF194
- Application:
- ELISA, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Rkhd2 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human RKHD2.The immunogen is located within amino acids 540 - 590 of Rkhd2.
- Uniprot:
- Q5U5Q3
- Synonyms:
- BM-013;MEX-3C;MEX3C variant 1;MEX3C variant 2;ring finger and KH domain containing 2;RING finger and KH domain-containing protein 2;RING finger protein 194;RING-type E3 ubiquitin transferase MEX3C;RKHD2;RNA-binding E3 ubiquitin-protein ligase MEX3C;RNA-binding protein MEX3C;RNF194
- Extra Details:
- Rkhd2, also known as MEX3C is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd2, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. It has been suggested that genetic variations in Rkhd2 may be associated with susceptibility to essential hypertension type 8. Rkhd3 and Rkhd4, but not Rkhd2, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover.
- Shipping Conditions:
- Blue Ice