GTX85355
PIG-Y antibody
Cannot supply to this region.
- SKU:
- GTX85355
- Additional Names:
- phosphatidylinositol glycan anchor biosynthesis class Y , HPMRS6 , PIG-Y
- Application:
- ELISA, WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- PIG-Y antibody was raised against a 16 amino acid synthetic peptide near the center of human PIG-Y.The immunogen is located within amino acids 50 - 100 of PIG-Y.
- Uniprot:
- Q3MUY2
- Synonyms:
- HPMRS6;phosphatidylinositol N-acetylglucosaminyltransferase subunit Y;phosphatidylinositol-glycan biosynthesis class Y protein;PIG-Y
- Extra Details:
- Glycosylphosphatidylinositol (GPI) lipid anchoring is an important post-translational modification of proteins that takes place in the endoplasmic reticulum. The synthesis of GPI is initiated by GPI-N-acetylglucosaminyltransferase (GPI-GnT), a complex of proteins including PIG-A, PIG-H, PIG-C, GPI1, and DPM2. PIG-Y, the mammalian homolog to yeast Eri1p, is also thought to be involved in the biosynthesis of GPI. The PIG-Y gene encodes two proteins, one of which arises from leaky scanning of the mRNA. This antibody only detects isoform 1 of PIG-Y. Despite its predicted molecular weight, PIG-Y often migrates at 28-30 kDa in SDS-PAGE.
- Shipping Conditions:
- Blue Ice