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  2. Polyclonal

GTX85241

TMEM16B antibody

Cannot supply to this region.

SKU:
GTX85241
Additional Names:
anoctamin 2 , C12orf3 , TMEM16B
Application:
ELISA, WB, IHC-P
Concentration:
1 mg/ml
Physical State:
Liquid
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:
Genetex
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS, 0.02% Sodium azide.
Immunogen:
TMEM16B antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human TMEM16B.The immunogen is located within the first 50 amino acids of TMEM16B.
Uniprot:
Q9NQ90
Synonyms:
anoctamin 2, calcium activated chloride channel;anoctamin-2;C12orf3;TMEM16B;Transmembrane protein 16B;transmembrane protein 16B (eight membrane-spanning domains)
Extra Details:
Calcium-activated chloride channels (CaCC) are present in many cell types and mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction. Subunits of these CaCC's include the transmembrane proteins TMEM16A and TMEM16B. TMEM16B is predicted to have eight transmembrane domains with both the amino and carboxy termini in the cytoplasm and is expressed in several tissues including olfactory sensory neurons as well as photoreceptors in mammalian retina. Like TMEM16A, TMEM16B is thought to form at least part of CaCC's but has different biophysical characteristics such as voltage dependence and unitary conductance.
Shipping Conditions:
Blue Ice