GTX85226
SIPA1L3 antibody
Cannot supply to this region.
- SKU:
- GTX85226
- Additional Names:
- signal induced proliferation associated 1 like 3 , CTRCT45 , SPAL3 , SPAR3
- Application:
- ELISA, WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- SIPA1L3 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human SIPA1L3.The immunogen is located within amino acids 80 - 130 of SIPA1L3.
- Uniprot:
- O60292
- Synonyms:
- CTRCT45;signal-induced proliferation-associated 1-like protein 3;SIPA1-like protein 3;SPA-1-like protein 3;SPAL3;SPAR3;spine-associated RapGAP 3
- Extra Details:
- Signal-induced proliferation associated-like protein 2 (SIPA1L3) is a member of the SIPA1 family of RapGAPs. SIPA1L3 was cloned as a novel molecular component of tight junctions and adherens junctions, suggesting that may function to balance Rap1 by counteracting RapGEFs. Recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice (3) and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is possible that SIPA1L3 plays other roles development and cell proliferation.
- Shipping Conditions:
- Blue Ice