GTX85224
PPAPDC1A antibody
Cannot supply to this region.
- SKU:
- GTX85224
- Additional Names:
- phospholipid phosphatase 4 , DPPL2 , PPAPDC1 , PPAPDC1A
- Application:
- ELISA, WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- PPAPDC1A antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human PPAPDC1A.The immunogen is located within the last 50 amino acids of PPAPDC1A.
- Uniprot:
- Q5VZY2
- Synonyms:
- diacylglycerol pyrophosphate like 2;diacylglycerol pyrophosphate phosphatase-like 2;DPPL2;phosphatidate phosphatase PPAPDC1A;phosphatidic acid phosphatase type 2 domain containing 1A;phosphatidic acid phosphatase type 2 domain-containing protein 1A;phospholipid phosphatase 4;PPAPDC1;PPAPDC1A
- Extra Details:
- Phosphatidate phosphatase (PAP) plays important role in lipid-signaling metabolism in eukaryotic cells. Two distinct types of PAP (PAP1 and PAP2) activity have been distinguished by their subcellular localization and differential sensitivity to N-ethylmaleimide(NEM) and Mg2+. A yeast diacylglycerol pyrophosphate (DGPP) phosphatase (DPP1) and mammalian DGPP phosphatase (PAP2) have been identified as Mg2+-independent and NEM-insensitive membrane-associated. PPAPDC1A (also known as DPPL2) and PPAPDC1B (DPPL1) form a novel type of Mg2+-independent and NEM-sensitive mammalian phosphatidate phosphatase showing broad substrate specificity. PPAPDC1A is preferentially expressed in endothelial cells. Studies of PPAPDC1A and PAP activity suggest that they may play a role in angiogenesis.
- Shipping Conditions:
- Blue Ice