GTX85222
PPAPDC2 antibody
Cannot supply to this region.
- SKU:
- GTX85222
- Additional Names:
- phospholipid phosphatase 6 , PDP1 , PPAPDC2 , PSDP , bA6J24.6
- Application:
- ELISA, WB, IF, ICC
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- PPAPDC2 antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus human PPAPDC2.The immunogen is located within amino acids 170 - 220 of PPAPDC2.
- Uniprot:
- Q8IY26
- Synonyms:
- bA6J24.6;PDP1;phosphatidic acid phosphatase type 2 domain containing 2;phosphatidic acid phosphatase type 2 domain-containing protein 2;phospholipid phosphatase 6;polyisoprenoid diphosphate phosphatase type 1;PPAP2 domain-containing protein 2;PPAPDC2;presqualene diphosphate phosphatase;PSDP
- Extra Details:
- PPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity. PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation. PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts. It is widely expressed in human tissues. Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase.
- Shipping Conditions:
- Blue Ice