GTX85212
TRESK antibody
Cannot supply to this region.
- SKU:
- GTX85212
- Additional Names:
- potassium two pore domain channel subfamily K member 18 , K2p18.1 , MGR13 , TRESK , TRESK-2 , TRESK2 , TRIK
- Application:
- ELISA, WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- TRESK antibody was raised against a 17 amino acid synthetic peptide from near the center of human TRESK.The immunogen is located within amino acids 210 - 260 of TRESK.
- Uniprot:
- Q7Z418
- Synonyms:
- K2p18.1;MGR13;potassium channel subfamily K member 18;potassium channel, subfamily K, member 18;potassium channel, two pore domain subfamily K, member 18;TRESK;TRESK-2;TRESK2;TRIK;TWIK-related individual K+ channel;TWIK-related individual potassium channel;TWIK-related spinal cord K+ channel;TWIK-related spinal cord potassium channel
- Extra Details:
- TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.
- Shipping Conditions:
- Blue Ice