GTX85155
NALP8 antibody
Cannot supply to this region.
- SKU:
- GTX85155
- Additional Names:
- NLR family pyrin domain containing 8 , CLR19.2 , NALP8 , NOD16 , PAN4
- Application:
- ELISA, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- NALP8 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human NALP8.The immunogen is located within amino acids 130 - 180 of NALP8.
- Uniprot:
- Q86W28
- Synonyms:
- CLR19.2;NACHT, leucine rich repeat and PYD containing 8;NACHT, LRR and PYD domains-containing protein 8;NALP8;NOD16;nucleotide-binding oligomerization domain protein 16;nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 8;PAN4;PYRIN and NACHT-containing protein 4
- Extra Details:
- NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP8 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting that NALP8 may be involved in reproduction. Surprisingly, NALP8 seems to be universal in mammals except for rodents, suggesting that the gene may have been lost during evolution.
- Shipping Conditions:
- Blue Ice