GTX85154
NALP10 antibody
Cannot supply to this region.
- SKU:
- GTX85154
- Additional Names:
- NLR family pyrin domain containing 10 , CLR11.1 , NALP10 , NOD8 , PAN5 , PYNOD
- Application:
- ELISA, WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- NALP10 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human NALP10.The immunogen is located within the first 50 amino acids of NALP10.
- Uniprot:
- Q86W26
- Synonyms:
- CLR11.1;NACHT, leucine rich repeat and PYD containing 10;NACHT, LRR and PYD domains-containing protein 10;NALP10;NOD8;nucleotide-binding oligomerization domain protein 8;nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 10;PAN5;PYNOD
- Extra Details:
- NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP10 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It was initially identified as PYNOD, an Apaf-1-like protein that binds to ASC, caspase-1 and IL-1b, inhibiting the autoprocessing of caspase-1, caspase-1-mediated IL-1b processing, and ASC aggregation. NALP10 is thus a potent regulator of apoptosis and inflammation.
- Shipping Conditions:
- Blue Ice