MD2 antibody [1A2E3]

Cannot supply to this region.

SKU:: GTX85121
Additional Names:: lymphocyte antigen 96 , ESOP-1 , MD-2 , MD2 , ly-96
Application:: ELISA, WB, IHC-P
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human, Mouse, Rat
Buffer:: PBS, 0.02% Sodium azide.
Immunogen:: Mouse monoclonal MD-2 antibody was raised against a recombinant protein corresponding to amino acids 2 to 160 of human MD-2.
Clone:: 1A2E3
Uniprot:: Q9Y6Y9
Synonyms:: ESOP-1;ly-96;lymphocyte antigen 96;MD-2;MD2;myeloid differentiation protein-2;protein MD-2
Extra Details:: MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.

Shipping Conditions:: Blue Ice