GTX85114
CDC42 antibody
Cannot supply to this region.
- SKU:
- GTX85114
- Additional Names:
- cell division cycle 42 , CDC42Hs , G25K , TKS
- Application:
- ELISA, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- 2-8[o]C
- Supplier:
- Genetex
- Host:
- Chicken/Avian
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- CDC42 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human CDC42.The immunogen is located within amino acids 40 - 90 of CDC42.
- Uniprot:
- P60953
- Synonyms:
- CDC42Hs;cell division control protein 42 homolog;dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD));dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD));G25K;G25K GTP-binding protein;growth-regulating protein;GTP binding protein, 25kDa;small GTP binding protein CDC42;TKS
- Extra Details:
- CDC42 is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to S. cerevisiae CDC42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. CDC42 is thought to regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. At least two isoforms of CDC42 are known to exist.
- Shipping Conditions:
- Blue Ice