GTX85065
MD1 antibody
Cannot supply to this region.
- SKU:
- GTX85065
- Additional Names:
- lymphocyte antigen 86 , MD-1 , MD1 , MMD-1 , dJ80N2.1
- Application:
- ELISA, WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- MD-1 antibody was raised against a 15 amino acid synthetic peptide from near the center of human MD-1.The immunogen is located within the last 50 amino acids of MD-1.
- Uniprot:
- O95711
- Synonyms:
- dJ80N2.1;ly-86;lymphocyte antigen 86;MD-1;MD-1, RP105-associated;MD1;MMD-1;protein MD-1
- Extra Details:
- Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD-1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.
- Shipping Conditions:
- Blue Ice