GTX85036
CAPS1 antibody
Cannot supply to this region.
- SKU:
- GTX85036
- Additional Names:
- calcium dependent secretion activator , CADPS1 , CAPS , CAPS1 , UNC-31
- Application:
- ELISA, WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- CAPS1 antibody was raised against a 21 amino acid synthetic peptide near the amino terminus of the human CAPS1.The immunogen is located within amino acids 90 - 140 of CAPS1.
- Uniprot:
- Q9ULU8
- Synonyms:
- Ca++-dependent secretion activator;Ca2+ dependent secretion activator;Ca2+-dependent activator protein for secretion;Ca2+-regulated cytoskeletal protein;CADPS1;calcium-dependent activator protein for secretion 1;calcium-dependent secretion activator 1;CAPS;CAPS-1;CAPS1;UNC-31
- Extra Details:
- CAPS1 and its related protein CAPS2 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles; CAPS-deficienct neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. CAPS1 acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate and is thought to be a specific regulator of large dense-core vesicle fusion. Numerous isoforms of CAPS1 are known to exist. This CAPS1 antibody is predicted to be specific to CAPS1 and not recognize CAPS2.
- Shipping Conditions:
- Blue Ice