GTX85025
SPRED2 antibody
Cannot supply to this region.
- SKU:
- GTX85025
- Additional Names:
- sprouty related EVH1 domain containing 2 , Spred-2
- Application:
- ELISA, WB
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- Spred2 antibody was raised against a 13 amino acid synthetic peptide near the center of the human Spred2.The immunogen is located within amino acids 140 - 190 of Spred2.
- Uniprot:
- Q7Z698
- Synonyms:
- Spred-2;sprouty protein with EVH-1 domain 2, related sequence;sprouty-related, EVH1 domain-containing protein 2
- Extra Details:
- Spred2 is a member of the Sprouty family, a group of proteins that act as negative regulators during development. Like Spred1, Spred2 acts by suppressing the phosphorylation and activation of Raf. The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis. Further studies have shown that expression levels of Spred1 and Spred2 proteins are inversely correlated with the incidence of tumor invasion and metastasis in human hepatocellular carcinoma (HHC), suggesting that these proteins could be useful as prognostic factors and therapeutic targets in HCC. At least two isoforms of Spred2 are known to exist. This Spred2 antibody is predicted to have no cross-reactivity to Spred1 or Spred3.
- Shipping Conditions:
- Blue Ice