Occludin antibody

Cannot supply to this region.

SKU:: GTX85016
Additional Names:: occludin , BLCPMG , PPP1R115 , PTORCH1
Application:: ELISA, WB, IHC-P
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: 2-8[o]C
Supplier:: Genetex
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: PBS, 0.02% Sodium azide.
Immunogen:: OCLN antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human OCLN.The immunogen is located within the last 50 amino acids of OCLN.
Uniprot:: Q16625
Synonyms:: BLCPMG;occludin;phosphatase 1, regulatory subunit 115;PPP1R115;PTORCH1
Extra Details:: Tight junctions act as a semi-permeable barrier to the transport of ions, solutes, and water and are considered to function as a fence that divides apical and basolateral domains of plasma membranes. Tight junctions coordinate a variety of signaling and trafficking molecules regulating cell differentiation, proliferation, and polarity and contain a number of junctional proteins including Occludin, Claudins, junctional adhesion molecules (JAMs), as well as multiple scaffold proteins. Occludin, the first identified component of tight junction strands, is thought function as a signal transmitter in multiple signaling pathways and can associate with multiple kinases and phosphatases such as PI3-kinase and protein phosphatases 1 and 2A. At least two isoforms of OCLN are known to exist.