GTX84999
NLRX1 antibody
Cannot supply to this region.
- SKU:
- GTX84999
- Additional Names:
- NLR family member X1 , CLR11.3 , DLNB26 , NOD26 , NOD5 , NOD9
- Application:
- ELISA, WB, IHC-P
- Concentration:
- 1 mg/ml
- Physical State:
- Liquid
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Supplier:
- Genetex
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.02% Sodium azide.
- Immunogen:
- NLRX1 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human NLRX1.The immunogen is located within amino acids 70 - 120 of NLRX1.
- Uniprot:
- Q86UT6
- Synonyms:
- caterpiller protein 11.3;CLR11.3;DLNB26;NLR family member X1;NOD-like receptor X1;NOD26;NOD5;NOD9;nucleotide-binding oligomerization domain protein 26;nucleotide-binding oligomerization domain protein 5;nucleotide-binding oligomerization domain protein 9;nucleotide-binding oligomerization domain, leucine rich repeat containing X1
- Extra Details:
- NOD5, also known as NLRX1, is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD5 localizes to the mitochondrial outer membrane and interacts with the virus-induced signaling adapter protein VISA. Unlike a subset of NOD-like receptors (NLRs) such as NOD1 and NOD2 which trigger pro-inflammatory cascades, and other NLRs that induce the caspase 1 inflammasome in response to immune challenges, NOD5 amplifies NF-kB and JNK pathways by inducing reactive oxygen species production.
- Shipping Conditions:
- Blue Ice