Hax1a antibody [9G6C6]

Cannot supply to this region.

SKU:: GTX84982
Additional Names:: HCLS1 associated protein X-1 , HCLSBP1 , HS1BP1 , SCN3
Application:: ELISA, WB
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human, Rat
Buffer:: PBS, 0.02% Sodium azide.
Immunogen:: Mouse monoclonal Hax1a antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human Hax1a.
Clone:: 9G6C6
Uniprot:: O00165
Synonyms:: HAX-1;HCLS1 (and PKD2) associated protein;HCLS1-associated protein X-1;HCLSBP1;HS1 binding protein;HS1-associating protein X-1;HS1-binding protein 1;HS1BP1;HSP1BP-1;SCN3
Extra Details:: The HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay on the basis of its ability to bind to the hemapoietic cell-specific protein 1 (HS-1). Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including the presence of BH1- and BH2-like domains. It has recently been shown to interact with HIV viral protein R (Vpr), a protein required for viral pathogenesis of HIV and linked to T-cell apoptosis through activation of caspases 3 and 9. Other studies indicate that Hax1-mediated processing of HtrA2 (also known as Omi) by the mitochondrial protease PARL allows survival of lymphocytes and neurons when cytokines are limiting. At least four isoforms of Hax1 are known to exist. This antibody is expected to recognize the longest isoform (Hax1a) as well as the shortest.

Shipping Conditions:: Blue Ice