Bcl-XL antibody [4A9]

Cannot supply to this region.

SKU:: GTX84834
Additional Names:: BCL2 like 1 , BCL-XL/S , BCL2L , BCLX , Bcl-X , PPP1R52
Application:: WB, IHC-P, IF, ICC
Concentration:: 0.25 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human, Mouse
Buffer:: PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Recombinant fragment expressed in E.coli corresponding to amino acids 1-212 of human Bcl-XL
Clone:: 4A9
Uniprot:: Q07817
Synonyms:: apoptosis regulator Bcl-X;bcl-2-like protein 1;Bcl-X;BCL-XL/S;BCL2L;BCLX;PPP1R52;protein phosphatase 1, regulatory subunit 52
Extra Details:: Potent inhibitor of cell death. Inhibits activation of caspases (By similarity). Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Isoform Bcl-X(S) promotes apoptosis.