CYP1A2 antibody [15E2]

Cannot supply to this region.

SKU:: GTX84638
Additional Names:: cytochrome P450 family 1 subfamily A member 2 , CP12 , CYPIA2 , P3-450 , P450(PA)
Application:: Flow Cytometry, WB, IHC-P, IF, ICC
Concentration:: 0.8 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Full length human recombinant protein of human CYP1A2 (NP_000752) produced in HEK293T cell.
Clone:: 15E2
Uniprot:: P05177
Synonyms:: aryl hydrocarbon hydroxylase;cholesterol 25-hydroxylase;CP12;CYPIA2;cytochrome P(3)450;cytochrome P450 1A2;cytochrome P450 4;cytochrome P450-P3;cytochrome P450, family 1, subfamily A, polypeptide 2;cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2;dioxin-inducible P3-450;flavoprotein-linked monooxygenase;hydroperoxy icosatetraenoate dehydratase;microsomal monooxygenase;P3-450;P450 form 4;P450(PA);xenobiotic monooxygenase
Extra Details:: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.

Shipping Conditions:: Blue Ice