LEMD3 antibody [3H2]

Cannot supply to this region.

SKU:: GTX84222
Additional Names:: LEM domain containing 3 , MAN1
Application:: WB, IP
Concentration:: 0.61 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Canine, Human
Buffer:: PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Full length human recombinant protein of human LEMD3 (NP_055134) produced in HEK293T cell.
Clone:: 3H2
Uniprot:: Q9Y2U8
Synonyms:: inner nuclear membrane protein Man1;integral inner nuclear membrane protein;LEM domain-containing protein 3;LEMD3/MKX fusion;MAN antigen 1;MAN1
Extra Details:: Can function as a specific repressor of TGF-beta, activin, and BMP signaling through its interaction with the R-SMAD proteins. Antagonizes TGF-beta-induced cell proliferation arrest.