NIT1 antibody [4D12]

Cannot supply to this region.

SKU:: GTX84042
Additional Names:: nitrilase 1
Application:: Flow Cytometry, WB, IHC-P, IF, ICC
Concentration:: 0.66 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human
Buffer:: PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Full length human recombinant protein of human NIT1 (NP_005591) produced in HEK293T cell.
Clone:: 4D12
Uniprot:: Q86X76
Synonyms:: deaminated glutathione amidase;dGSH amidase;Nitrilase homolog 1
Extra Details:: Play a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells | this effect is additive to the tumor suppressor activity of FHIT. it is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2.