NUMB antibody [1A7]

Cannot supply to this region.

SKU:: GTX83974
Additional Names:: NUMB endocytic adaptor protein , C14orf41 , S171 , c14_5527
Application:: Flow Cytometry, WB, IF, ICC
Concentration:: 0.6 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Canine, Human
Buffer:: PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Full length human recombinant protein of human NUMB (NP_003735) produced in HEK293T cell.
Clone:: 1A7
Uniprot:: P49757
Synonyms:: c14_5527;C14orf41;h-Numb;numb homolog;protein numb homolog;Protein S171;S171
Extra Details:: Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.