PDX1 antibody [2A12]

Cannot supply to this region.

SKU:: GTX83919
Additional Names:: pancreatic and duodenal homeobox 1 , GSF , IDX-1 , IPF1 , IUF1 , MODY4 , PAGEN1 , PDX-1 , STF-1
Application:: WB, IHC-P, IF, ICC
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Human, Mouse
Buffer:: PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Full length human recombinant protein of human PDX1 (NP_000200) produced in E.coli.
Clone:: 2A12
Uniprot:: P52945
Synonyms:: glucose-sensitive factor;GSF;IDX-1;Insulin promoter factor 1;insulin promoter factor 1, homeodomain transcription factor;insulin upstream factor 1;IPF-1;IPF1;islet/duodenum homeobox-1;IUF-1;IUF1;MODY4;PAGEN1;pancreas/duodenum homeobox protein 1;pancreatic-duodenal homeobox factor 1;PDX-1;somatostatin transcription factor 1;somatostatin-transactivating factor 1;STF-1
Extra Details:: Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell.

Shipping Conditions:: Blue Ice