PKMYT1 antibody [2B4]

Cannot supply to this region.

SKU:: GTX83875
Additional Names:: protein kinase, membrane associated tyrosine/threonine 1 , MYT1 , PPP1R126
Application:: Flow Cytometry, WB, IF, ICC
Concentration:: 1 mg/ml
Physical State:: Liquid
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Supplier:: Genetex
Host:: Mouse
Reactivities:: Canine, Human, Mouse, Rat
Buffer:: PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
Immunogen:: Full length human recombinant protein of human PKMYT1 (NP_004194) produced in HEK293T cell.
Clone:: 2B4
Uniprot:: Q99640
Synonyms:: membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase;MYT1;myt1 kinase;PPP1R126;protein phosphatase 1, regulatory subunit 126
Extra Details:: Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development.